罗海
博士,副教授,博士生导师
分析化学，质谱科学和技术
电话: +86-10-62751499
传真: +86-10-62751708
电子信箱:hluo@pku.edu.cn
教育背景:
2000，美国普渡大学，分析化学，博士(导师：R. Graham Cooks, Michael J. Weaver)
1994，美国西弗吉尼亚大学，物理化学，硕士(导师：Naresh S. Dalal)
1990，中国科学技术大学，高分子化学，学士(导师：汪月生,张其锦)
工作经历:
2005 -至今，北京大学化学与分子工程学院，副教授
2002 - 2004，美国雅培公司生命研究中心，研究员
2000 - 2002，美国太平洋西北国家实验室，博士后
1990 - 1992，中国科学院大连化学物理研究所，研习员
教学工作：
分析化学Seminar（研究生），分析化学（B）以及实验课（本科生）
研究领域和兴趣：
1.质谱离子化技术和分析方法的发展及应用
2.新型质谱离子源上的原位化学反应和应用
3.非共价复合物和超分子团簇离子的气相化学和表征
主持国家自然科学基金项目情况：
1.国家自然科学基金面上项目，21874002，新型电化学-质谱平台及其在电化学反应机理
研究中的应用，2019/01-2022/12，64万元，在研
2.国家自然科学基金应急管理项目，21445005，快速蒸发多通道旋转质谱离子源的设计、
构建和在生物组织诊断上的基础应用研究，2015/01-2015/12，10万元，已结题，主持
3.国家自然科学基金面上项目，21075005，基于脲嘧啶和胸腺嘧啶五联体的新型非共价
自组装体系的研究，2011/01-2013/12，35万元，已结题，主持
4.国家自然科学基金科学仪器基础研究专项基金项目，20727002，喷雾辅助激光解吸环境
电离源的设计、构建和基础应用研究，2008/01-2010/12，160万元，已结题，主持
5.国家自然科学基金面上项目，20575006，电喷雾电离质谱方法在表面和生化分析中的应
用基础研究，2006/01-2008/12，28万元，已结题，主持
代表性论文：
(1) Ran Qiu#, Xin Zhang#,Hai Luo*, Yuanhua Shao*, Mass spectrometric snapshots for
electrochemical reactions, Chemical Science, 2016, 7(11): 6684-6688.
(2) Ran Qiu, Jiamu Sun, Chengsen Zhang*,Hai Luo*, Heterogeneous cation induced clusters
formed at surfaces of micro-droplets, RSC Advances, 2016, 6(53): 47997-48000.(3) Ran Qiu, Chengsen Zhang*, Zhen Qin,Hai Luo*,A multichannel rotating electrospray
ionization mass spectrometry (MRESI): instrumentation and plume interactions, RSC
Advances, 2016, 6(43): 36615-36622.
(4) Ran Qiu#, Jiamu Sun#, Xin Zhang, Wenbo Zhao, Zhen Qin*,Hai Luo*, Isomer
differentiation through supramolecular self-assembly in microdroplets of milliseconds
life-time, Analyst, 2016, 141(5): 1641-1644.
(5) Ran Qiu,Hai Luo*, Copper (I)-triazole dimer formation and rate acceleration in in-source
click reaction, RSC Advances, 2015, 5(116): 96213-96221.
(6)任昕昕,邱然,罗海*,高电压辅助激光解吸附离子化质谱中盐效应的研究,分析化学，
2014，42(11): 1697-1701.
(7) Wenbo Zhao, Zhen Qin, Chengsen Zhang, Meiping Zhao*,Hai Luo*, A label-free double
amplification system for sensitive detection of single-stranded DNA and thrombin by liquid
chromatography-mass spectrometry, Chemical Communications, 2014, 50(69): 9846-9848.
(8) Ran Qiu,Hai Luo*, Reaction and detection click in high-voltage assisted laser desorption
ionization mass spectrometry, Analyst, 2014, 139(15): 3706-3708.
(9) Jiamu Sun, Zhen Qin, Jia Liu, Chengsen Zhang,Hai Luo*, Highly sensitive and specific
detection of histamine via the formation of a self-assembled magic number cluster with
thymine by mass spectrometry, Analyst, 2014, 139(12): 3154-3159.
(10) Zhen Qin, Bo Qiu, Jiamu Sun, Wenbo Zhao,Hai Luo*, Protonated primary amines induced
thymine quintets studied by electrospray ionization mass spectrometry and density
functional theory calculations, Journal of Mass Spectrometry, 2014, 49(4): 266-273.
(11) Xinxin Ren, Jia Liu, Chengsen Zhang, Jiamu Sun,Hai Luo*, Signal enhancement of
carboxylic acids by inclusion with β-cyclodextrin in negative high-voltage-assisted laser
desorption ionization mass spectrometry, Rapid Communications in Mass Spectrometry,
2014, 28(1): 115-122.
(12) Xinxin Ren, Jia Liu, Chengsen Zhang,Hai Luo*, Direct analysis of samples under
ambient condition by high-voltage assisted laser desorption ionization mass spectrometry
in both positive and negative ion mode, Rapid Communications in Mass Spectrometry,
2013, 27(5): 613-620.
(13) Jia Liu, Chengsen Zhang, Jiamu Sun, Xinxin Ren,Hai Luo*, Laser desorption dual-spray
post-ionization mass spectrometry for direct analysis of samples via two informative
channels, Journal of Mass Spectrometry, 2013, 48(2): 250-254.
(14) REN Xin-Xin, LIU Jia, ZHANG Cheng-Sen,LUO Hai*, Rapid and direct analysis of
active ingredients in tablets using atmospheric pressure laser desorption ionization mass
spectrometry, Chinese Journal of Analytical Chemistry, 2013, 41(3): 366-370.
(15) Zhen Qin, Jia Liu, Bo Qiu,Hai Luo*, Reactive desorption electrospray ionization mass
spectrometry of self-assembled quintets of uracil and its homologues, Journal of Mass
Spectrometry, 2012, 47(5): 552-554.
(16) Jia Liu, Chengsen Zhang, Jiamu Sun,Hai Luo*, Unexpected complexation reaction during
analysis of proteins using laser desorption spray post-ionization mass spectrometry, Analyst,
2012, 137(8): 1764-1767.
(17) Bo Qiu, Zhen Qin, Jia Liu,Hai Luo*, Thymine quintets and their higher order assemblies
studied by electrospray ionization mass spectrometry and theoretical calculation, Journal of
Mass Spectrometry, 2011, 46(6): 587-594.(18) Congfang Lai, Guangxin Lin, Wenyue Wang,Hai Luo*, Absolute configurations and
stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal, Chirality,
2011, 23(7): 487-494.
(19) Jia Liu, Bo Qiu,Hai Luo*, Fingerprinting of yogurt products by laser desorption spray
post-ionization mass spectrometry, Rapid Communications in Mass Spectrometry, 2010,
24(9): 1365-1370.
(20) Guangxin Lin, Jing Zhang, Yu Zeng,Hai Luo*, Yinsheng Wang*, Conformation
dependent formation of theG[8-5]U intrastrand cross-link in 5-bromouracil-containing
G-quadruplex DNA induced by UVA irradiation, Biochemistry, 2010, 49(11): 2346-2350.
(21) Bo Qiu, Jia Liu, Zhen Qin, Guanbo Wang, andHai Luo*, Quintets of uracil and thymine:
a novel structure of nucleobase self-assembly studied by electrospray ionization mass
spectrometry, Chemical Communications, 2009, (20): 2863-2865.
(22) Bo Qiu, andHai Luo*, Desorption electrospray ionization mass spectrometry of DNA
nucleobases: implications for a liquid film model, Journal of Mass Spectrometry, 2009,
44(5): 772-779.
(23) Congfang Lai, Huachuan Cao, John E. Hearst, Laurence Corash,Hai Luo*, and Yinsheng
Wang*, Quantitative analysis of DNA interstrand cross-links and monoadducts formed in
human cells induced by psoralens and UVA irradiation, Analytical Chemistry, 2008, 80(22):
8790-8798.
(24)薛震，邱波，林广欣，赖丛芳，罗海*,解吸电喷雾电离技术,化学进展, 2008, 20(4):
594-601.
已授权专利：
(1)张成森，罗海，邱然，一种多通道旋转萃取电喷雾离子化质谱分析离子源，
2015.01.14，中国，ZL201210202005.3
(2)张成森，罗海，多通道旋转电喷雾离子化质谱分析离子源，
2014.07.02，中国, ZL201110422357.5
(3)张成森，罗海，刘佳，秦震，质谱多通道旋转电喷雾离子源，
2013.03.06，中国，ZL201110240135.1
(4)张成森，罗海，任昕昕，刘佳，一种高压辅助激光解吸离子化质谱分析离子源，
2012.07.18，中国，ZL201120498921.7
(5)张成森，罗海，秦震，刘佳，质谱双离子源安装平台装置，
2011.12.07，中国，ZL201120134522.2
(6)罗海，刘佳，邱波，质谱离子传输管外延长接口装置，
2010.05.12，中国，ZL200920108393.2
