李 娜
博士，教授，博士生导师
分析化学
电话：62761187
传真：62751708
电子信箱：lina@pku.edu.cn
学术简历：
1988、1991和1994年先后获北京大学理学学士、硕士和博士学位
1994-1998年，北京大学化学学院工作
1999-2000，美国堪萨斯大学药化系CDDR博士后
2000至今 北京大学化学学院工作
教学：
主讲定量分析化学（英语），教育部2008年度双语教学示范课程
主讲分析化学系列小班讨论课
2008年北京市教育教学成果一等奖
2011年北京市高等教育精品教材
出版教材：
1. Quantitative Chemical Analysis (英文)，北京大学出版社，2009 (主编)
2. 分析化学I（电子课件），北京大学出版社, 2007(主编)
3. 分析化学教程学习指导，北京大学出版社, 2006 (参编)
4. 分析化学教程，北京大学出版社, 2005 (参编)
5. 超越分子前沿，科学出版社，2004 (参译)
研究领域和兴趣：
光学传感新原理、新方法。主要兴趣为：
基于单颗粒金属纳米材料光谱（荧光、局域表面等离子体共振吸收/散射）的生物传感。
2012年以来发表的主要学术论文：
1. Tian Li, Xi Wu, Guangyu Tao, Haoyan Yin, Junlong Zhang, Feng Liu, Na Li*
A simple and non-amplification platform for femtomolar DNA and microRNA detection by combining automatic gold nanoparticle enumeration with target-induced strand-displacement
Biosens. Bioelectron. 2018, 105, 137-142
2. Xiaojing Pei, Tiancheng Lai, Guangyu Tao, Hu Hong, Feng Liu, Na Li*
Ultra-specific multiplexeddetection of low-abundance single-nucleotide variants by combining masking tactic with fluorescent nanoparticle counting
Anal. Chem. 2018, 90, 4226-4233
3. Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu, Xiao Xu*, Na Li*
Multiplexed Detection of Attomole Nucleic Acids Using Fluorescent Nanoparticle Counting Platform
Anal. Chem. 2018, 90, 1376-1383
4. Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu, Na Li
How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoclusters
Nano Res. 2017, 11, 223-2247
5. Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu, Na Li*.
Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety
Chem. Eur. J. 2017, 23, 10893-10900
6. Runyun Lin, Chenxi Li, Yang Chen, Feng Liu, Na Li*
Metal-enhanced fluorescence in biosensing applications, "Surface Plasmon Enhanced, Coupled and Controlled Fluorescence", 2017, Edited by Geddes, C. D., Wiley, NJ. (Invited chapter)
7. Wu, Xi, Tian Li, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu, Na Li.
Universal and Enzyme-Free Immunoassay Platform for Biomarker Detection Based on Gold Nanoparticle Enumeration with a Dark-Field Microscope.
Analyst, 2017, 142, 4201-4205
8. Tian Li, Xi Wu, Feng Liu, Na Li*.
Analytical Methods Based on the Light-Scattering of Plasmonic Nanoparticles at the Single Particle Level with Dark-Field Microscopy Imaging
Analyst, 2017, 142, 248-256
9. Chenxi Li, Yixin Li, Yang Chen, Ruoyun Lin, Tian Li, Feng Liu, Na Li*
Modulating the DNA strand-displacement kinetics with the one-sided remote toehold design for differentiation of single-base mismatched DNA
RSC Adv. 2016, 6, 74913-74916
10. Yang Chen, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu, Na Li*
Pre-Incubation of Auric Acid with DNA Is Unnecessary for the Formation of DNA-Templated Gold Nanoclusters
Chem.-an Asian J. 2016, 11, 1677-1681
11. Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu, Na Li*
Nonamplification Sandwich Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field Microscope
Anal. Chem. 2016, 88, 4188-4191
12. Xiao Xu, Tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu, Na Li*
Automatic enumeration of gold nanomaterials at single particle level
Anal. Chem. 2015, 87, 2576-2581
13. Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu, Bin Xia*, Feng Liu, Na Li*
Modulating fluorescence anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational design of DNA-recognition based applications
Anal. Chem. 2015, 87, 2748-2754
14. Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,* Na Li*
A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced fluorescence modality
Chem. Commun. 2014, 50, 13373-13376
15. Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu, Na Li*
Fast and quantitative differentiation of single-base mismatched DNA by initial reaction rate of catalytic hairpin assembly
Biosens. Bioelectron. 2014, 60, 57-63
16. Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang, Na Li*
A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design
Biosens. Bioelectron. 2014, 52, 367-373
17. Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang, Na Li*
Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction
Biosens. Bioelectron. 2013, 41, 569-575
18. Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu, Na Li*
Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter
Anal. Chem. 2012, 84, 9721-9728
19. Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu, Na Li*
The homogeneous Fluorescence Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxy fluorescein-labeled DNA Aptamer
Biosens. Bioelectron. 2012, 32, 148-154
